ZBTB7B antibody

Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes (By similarity) .

Zinc finger and BTB domain-containing protein 7B|Krueppel-related zinc finger protein cKrox (hcKrox) |T-helper-inducing POZ/Krueppel-like factor|Zinc finger and BTB domain-containing protein 15|Zinc finger protein 67 homolog (Zfp-67) |Zinc finger protein 857B|Zinc finger protein Th-POK|ZBTB7B|ZBTB15|ZFP67|ZNF857B