YME1L1 antibody
Product Specifications
Background
YME1L1 (ATP-dependent zinc metalloprotease) is also named as FTSH1, YME1L, Meg-4, PAMP. YME1L1 plays a phylogenetically conserved role in mitochondrial protein metabolism.It also ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. YME1L1 can prevent mitochondrial DNA inserting into nuclear. It has 3 isoforms produced by alternative splicing with the molecular weight of 86 kDa, 80 kDa and 76 kDa.
Synonyms
ATP-dependent zinc metalloprotease YME1L1|ATP-dependent metalloprotease FtsH1|Meg-4|Presenilin-associated metalloprotease (PAMP) |YME1-like protein 1|YME1L1|FTSH1|YME1L
Gene ID
10730
UniProt
Q96TA2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
YME1-like 1
Target
YME1L1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IF: 1:10-1:100; IHC: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
86 kDa, 60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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