YAP1 antibody
Product Specifications
Background
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
Transcriptional coactivator YAP1 (Yes-associated protein 1) |Protein yorkie homolog|Yes-associated protein YAP65 homolog|YAP1|YAP65
Gene ID
10413
UniProt
P46937
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Yes-associated protein 1, 65kDa
Target
YAP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Stem Cells, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; IP: 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
Immunogen Sequence
350-504aa
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