XRCC4 antibody
Product Specifications
Background
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.
Synonyms
DNA repair protein XRCC4 (hXRCC4)|X-ray repair cross-complementing protein 4|Protein XRCC4, C-terminus (XRCC4/C)|XRCC4
Gene ID
7518
UniProt
Q13426
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
X-ray repair complementing defective repair in Chinese hamster cells 4
Target
XRCC4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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