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XBP1 antibody

Product Specifications

Background

X-box-binding protein 1(XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa.

Synonyms

X-box-binding protein 1 (XBP-1)|Tax-responsive element-binding protein 5 (TREB-5)|X-box-binding protein 1, cytoplasmic form|X-box-binding protein 1, luminal form|XBP1|TREB5|XBP2

Gene ID

7494

UniProt

P17861

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

X-box binding protein 1

Target

XBP1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB,IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:1000; IHC: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

29 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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