XBP1 antibody
Product Specifications
Background
X-box-binding protein 1 (XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa. This antibody specially recognizes the XBP1S isoform.
Synonyms
X-box-binding protein 1 (XBP-1) |Tax-responsive element-binding protein 5 (TREB-5) |X-box-binding protein 1, cytoplasmic form|X-box-binding protein 1, luminal form|XBP1|TREB5|XBP2
Gene ID
7494
UniProt
P17861
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
X-box binding protein 1
Target
XBP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB,IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:1000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
P17861-2, A synthetic peptide in C termainal
Curated Selection
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