WWOX antibody
Product Specifications
Background
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity) . May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF) -mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Synonyms
WW domain-containing oxidoreductase|Fragile site FRA16D oxidoreductase|Short chain dehydrogenase/reductase family 41C member 1|WWOX|FOR|SDR41C1|WOX1
Gene ID
51741
UniProt
Q9NZC7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
WW domain containing oxidoreductase
Target
WWOX
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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