VTA1 antibody
Product Specifications
Background
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity) . Involved in HIV-1 budding.
Synonyms
Vacuolar protein sorting-associated protein VTA1 homolog|Dopamine-responsive gene 1 protein (DRG-1) |LYST-interacting protein 5 (LIP5) |SKD1-binding protein 1 (SBP1) |VTA1|C6orf55
Gene ID
51534
UniProt
Q9NP79
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Vps20-associated 1 homolog
Target
VTA1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:10000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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