VPS54 antibody
Product Specifications
Background
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:18367545). Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling(PubMed:25799061).
Synonyms
Vacuolar protein sorting-associated protein 54|Hepatocellular carcinoma protein 8|Tumor antigen HOM-HCC-8|Tumor antigen SLP-8p|VPS54|HCC8
Gene ID
51542
UniProt
Q9P1Q0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
vacuolar protein sorting 54 homolog
Target
VPS54
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000;IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
111 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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