USP22 antibody
Product Specifications
Background
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
Synonyms
Ubiquitin carboxyl-terminal hydrolase 22|Deubiquitinating enzyme 22|Ubiquitin thioesterase 22|Ubiquitin-specific-processing protease 22|USP22|KIAA1063|USP3L
Gene ID
23326
UniProt
Q9UPT9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ubiquitin specific peptidase 22
Target
USP22
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
66 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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