GUCA2B antibody
Product Specifications
Background
Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension (EH) .
Synonyms
Guanylate cyclase activator 2B|Guanylate cyclase C-activating peptide 2 Alternative names: Guanylate cyclase C-activating peptide II (GCAP-II) |Uroguanylin (UGN) |GUCA2B
Gene ID
2981
UniProt
Q16661
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Guanylate cyclase activator 2B (uroguanylin)
Target
GUCA2B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200; IF:1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
12 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC
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