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GUCA2B antibody

Product Specifications

Background

Uroguanylin, also named as GUCA2B, is a candidate intestinal natriuretic hormone that controls the sodium and water balance between the intestine and the kidneys. It has been reported that the uroguanylin knockout mouse exhibits elevated blood pressure. Therefore, the GUCA2B gene is thought to be a susceptibility gene for essential hypertension (EH) .

Synonyms

Guanylate cyclase activator 2B|Guanylate cyclase C-activating peptide 2 Alternative names: Guanylate cyclase C-activating peptide II (GCAP-II) |Uroguanylin (UGN) |GUCA2B

Gene ID

2981

UniProt

Q16661

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Guanylate cyclase activator 2B (uroguanylin)

Target

GUCA2B

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF, IHC

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IF:1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

12 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF, IHC

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