UNG antibody
Product Specifications
Background
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Synonyms
Uracil-DNA glycosylase (UDG)|UNG|DGU|UNG1|UNG15
Gene ID
7374
UniProt
P13051
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
uracil-DNA glycosylase
Target
UNG
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Purification
Immunogen affinity purified
Dilution
WB: 1:1000 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa, 40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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