UNC5D-Specific antibody
Product Specifications
Background
UNC5D, also named as KIAA1777 and UNC5H4, belongs to the unc-5 family. It is a receptor for netrin. It may be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5D.
Synonyms
Netrin receptor UNC5D|Protein unc-5 homolog 4|Protein unc-5 homolog D|UNC5D|KIAA1777|UNC5H4
UniProt
Q6UXZ4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Unc-5 homolog D (C. elegans)
Target
UNC5D
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Frequently Asked Questions
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