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CMPK1 antibody

Product Specifications

Background

Pyrimidine nucleoside monophosphate kinase [UMP/CMP kinase (UMP/CMPK) ] (CMPK1) is also named as CMK, CMPK, UCK, UMK, UMPK and belongs to the adenylate kinase family. It plays a crucial role in the formation of UDP, CDP, and dCDP, which are required for cellular nucleic acid synthesis (PMID:11912132) . CMPK1 can use a broad spectrum of phosphate donors but the best phosphate donors are ATP and dATP. The longest deduced protein contains 228 amino acids and has a calculated molecular mass of 26 kD. However, translation likely begins at the second initiation methionine, resulting in a protein of 196 amino acids (PMID:10462544) . The shorter form is the endogenously translated protein (PMID:11912132) .

Synonyms

UMP-CMP kinase|Deoxycytidylate kinase (CK, dCMP kinase) |Nucleoside-diphosphate kinase|Uridine monophosphate/cytidine monophosphate kinase (UMP/CMP kinase, UMP/CMPK) |CMPK1|CMK|CMPK|UCK|UMK|UMPK

UniProt

P30085

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic

Target

CMPK1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

26 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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