UBE2B antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Ubiquitin-conjugating enzyme E2 B|E2 ubiquitin-conjugating enzyme B|RAD6 homolog B (HR6B, hHR6B) |Ubiquitin carrier protein B|Ubiquitin-conjugating enzyme E2-17 kDa|Ubiquitin-protein ligase B|UBE2B|RAD6B|UBCH1