UACA antibody
Product Specifications
Background
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity) . Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility. Interaction with ARF6 may modulate cell shape and motility after injury. May be involved in multiple neurite formation (By similarity) .
Synonyms
Uveal autoantigen with coiled-coil domains and ankyrin repeats|UACA|KIAA1561
Gene ID
55075
UniProt
Q9BZF9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Target
UACA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:10000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
163 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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