TYW1B antibody
Product Specifications
Background
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity) .
Synonyms
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B|Radical S-adenosyl methionine and flavodoxin domain-containing protein 2|tRNA wybutosine-synthesizing protein 1 homolog B|TYW1B|RSAFD2
Gene ID
441250
UniProt
Q6NUM6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
TRNA-yW synthesizing protein 1 homolog B (non-protein coding)
Target
TYW1B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
77 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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