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TYW1B antibody

Product Specifications

Background

Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity) .

Synonyms

S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B|Radical S-adenosyl methionine and flavodoxin domain-containing protein 2|tRNA wybutosine-synthesizing protein 1 homolog B|TYW1B|RSAFD2

Gene ID

441250

UniProt

Q6NUM6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

TRNA-yW synthesizing protein 1 homolog B (non-protein coding)

Target

TYW1B

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

77 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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