TXNRD2 antibody
Product Specifications
Background
This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms
Thioredoxin reductase 2, mitochondrial|Selenoprotein Z (SelZ)|TR-beta|Thioredoxin reductase TR3|TXNRD2|KIAA1652|TRXR2
Gene ID
10587
UniProt
Q9NNW7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
thioredoxin reductase 2
Target
TXNRD2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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