TWIST2 antibody
Product Specifications
Background
Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism (By similarity) . Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.
Synonyms
Twist-related protein 2|Class A basic helix-loop-helix protein 39 (bHLHa39) |Dermis-expressed protein 1 (Dermo-1) |TWIST2|BHLHA39|DERMO1
Gene ID
117581
UniProt
Q8WVJ9
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Twist homolog 2
Target
TWIST2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Stem Cells, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21 kDa, 65 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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