TULP3 antibody
Product Specifications
Background
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A-and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.
Synonyms
Tubby-related protein 3|Tubby-like protein 3|TULP3|TUBL3
Gene ID
7289
UniProt
O75386
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tubby like protein 3
Target
TULP3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP, IF
Field of Research
Neuroscience, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IHC: 1:20-1:200; IP: 1:200-1:1000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP, IF
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