TNFAIP6 antibody
Product Specifications
Background
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
Synonyms
Tumor necrosis factor-inducible gene 6 protein|Hyaluronate-binding protein|TNF-stimulated gene 6 protein (TSG-6)|Tumor necrosis factor alpha-induced protein 6 (TNF alpha-induced protein 6)|TNFAIP6|TSG6
Gene ID
7130
UniProt
P98066
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
tumor necrosis factor, alpha-induced protein 6
Target
TNFAIP6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cardiovascular, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
41 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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