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TRPC4 antibody

Product Specifications

Background

Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.

Synonyms

Short transient receptor potential channel 4 (TrpC4)|Trp-related protein 4 (hTrp-4, hTrp4)|TRPC4

Gene ID

7223

UniProt

Q9UBN4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

transient receptor potential cation channel, subfamily C, member 4

Target

TRPC4

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Neuroscience, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

112 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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