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TRMT5 antibody

Product Specifications

Background

Involved in mitochondrial tRNA methylation (PubMed:26189817) . Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

Synonyms

TRNA (guanine (37) -N1) -methyltransferase|M1G-methyltransferase|tRNA [GM37] methyltransferase|tRNA methyltransferase 5 homolog|TRMT5|KIAA1393|TRM5

Gene ID

57570

UniProt

Q32P41

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

TRM5 tRNA methyltransferase 5 homolog

Target

TRMT5

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

58 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

Frequently Asked Questions

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