TRIP13 antibody

Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks(DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes(By similarity).

Pachytene checkpoint protein 2 homolog|Human papillomavirus type 16 E1 protein-binding protein (16E1-BP, HPV16 E1 protein-binding protein)|Thyroid hormone receptor interactor 13|Thyroid receptor-interacting protein 13 (TR-interacting protein 13, TRIP-13)|TRIP13|PCH2