TRIP10 antibody

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity) . Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

Cdc42-interacting protein 4|Protein Felic|Salt tolerant protein (hSTP) |Thyroid receptor-interacting protein 10 (TR-interacting protein 10, TRIP-10) |TRIP10|CIP4|STOT|STP