TRIM6 antibody
Product Specifications
Background
E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (By similarity) . Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response (PubMed:24882218) .
Synonyms
Tripartite motif-containing protein 6|RING finger protein 89|RING-type E3 ubiquitin transferase TRIM6|TRIM6|RNF89
Gene ID
117854
UniProt
Q9C030
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Tripartite motif-containing 6
Target
TRIM6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB
Immunogen Sequence
229-422
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