TRIM23 antibody

Acts as an E3 ubiquitin-protein ligase. In the presence of the human cytomegalovirus (HCMV) protein UL144, participates in 'Lys-63'-linked auto-ubiquitination of TRAF6 resulting in the virally controlled activation of NF-kappa-B at early time of infection. The C-terminus can act as an allosteric activator of the cholera toxin catalytic subunit.

E3 ubiquitin-protein ligase TRIM23|ADP-ribosylation factor domain-containing protein 1|GTP-binding protein ARD-1|RING finger protein 46|RING-type E3 ubiquitin transferase TRIM23|Tripartite motif-containing protein 23|TRIM23|ARD1|ARFD1|RNF46