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TRIM22 antibody

Product Specifications

Background

Interferon-induced antiviral protein involved in cell innate immunity. The antiviral activity could in part be mediated by TRIM22-dependent ubiquitination of viral proteins. Plays a role in restricting the replication of HIV-1, encephalomyocarditis virus (EMCV) and hepatitis B virus (HBV) . Acts as a transcriptional repressor of HBV core promoter. May have E3 ubiquitin-protein ligase activity.

Synonyms

E3 ubiquitin-protein ligase TRIM22|50 kDa-stimulated trans-acting factor|RING finger protein 94|RING-type E3 ubiquitin transferase TRIM22|Staf-50|Tripartite motif-containing protein 22|TRIM22|RNF94|STAF50

Gene ID

10346

UniProt

Q8IYM9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Tripartite motif-containing 22

Target

TRIM22

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Epigenetics, Immunology, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:1000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

52 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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