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TFF1 antibody

Product Specifications

Background

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Synonyms

Trefoil factor 1|Breast cancer estrogen-inducible protein|PNR-2|Polypeptide P1.A (hP1.A) |Protein pS2|TFF1|BCEI|PS2

Gene ID

7031

UniProt

P04155

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Trefoil factor 1

Target

TFF1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cancer, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:1000; IHC: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

12 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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