TARBP2 antibody
Product Specifications
Background
TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC) . Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs.
Synonyms
RISC-loading complex subunit TARBP2|TAR RNA-binding protein 2|Trans-activation-responsive RNA-binding protein|TARBP2|TRBP
Gene ID
6895
UniProt
Q15633
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
TAR (HIV-1) RNA binding protein 2
Target
TARBP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
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