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TAGLN antibody

Product Specifications

Background

The transgelin family is a group of proteins that belong to 22kd actin-related calponin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgelin 1 protein. It can cross-react with other two transgelins based on the sequence similarity.

Synonyms

Transgelin|22 kDa actin-binding protein|Protein WS3-10|Smooth muscle protein 22-alpha (SM22-alpha) |TAGLN|SM22|WS3-10

Gene ID

6876

UniProt

Q01995

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Transgelin

Target

TAGLN

Clonality

Monoclonal

Isotype

IgG1

Applications

ELISA, WB, IHC

Field of Research

Neuroscience, Stem Cells, Cardiovascular

Purification

Protein A+G purification

Dilution

WB: 1:1000-1:10000; IHC: 1:20-1:400

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

22 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

4B8

Tested Applications

ELISA, WB, IHC

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