TAGLN antibody
Product Specifications
Background
The transgelin family is a group of proteins that belong to 22kd actin-related calponin superfamily. Of all three isoforms, transgelin 1 is the best characterized. Transgelin 1, also known as SM22alpha, is a specific marker for differentiated smooth muscle cells. Transgelin 2, also known as SM22 beta, is expressed by both smooth muscle and non-smooth muscle cells in a temporally and spatially regulated pattern. Trangenlin 3, also known as NP25, is only found in highly differentiated neuronal cells. This antibody was generated against full length transgelin 1 protein. It can cross-react with other two transgelins based on the sequence similarity.
Synonyms
Transgelin|22 kDa actin-binding protein|Protein WS3-10|Smooth muscle protein 22-alpha (SM22-alpha)|TAGLN|SM22|WS3-10
Gene ID
6876
UniProt
Q01995
Host
Mouse
Reactivity
Human, Mouse
Immunogen
transgelin
Target
TAGLN
Clonality
Monoclonal
Isotype
IgG1
Clone
4B8
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Stem Cells, Cardiovascular
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000; IHC: 1:20-1:400
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
22 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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