TTF1-Specific antibody
Product Specifications
Background
TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.
Synonyms
Transcription termination factor 1 (TTF-1) |RNA polymerase I termination factor|Transcription termination factor I (TTF-I) |TTF1
Gene ID
7270
UniProt
Q15361
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Transcription termination factor, RNA polymerase I
Target
TTF1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB
Field of Research
Cancer, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:10000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
43 kDa, 66 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
7C4
Tested Applications
ELISA, WB
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