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TRAF7 antibody

Product Specifications

Background

E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3. Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators. Induces apoptosis when overexpressed.

Synonyms

E3 ubiquitin-protein ligase TRAF7|RING finger and WD repeat-containing protein 1|RING finger protein 119|RING-type E3 ubiquitin transferase TRAF7|TNF receptor-associated factor 7|TRAF7|RFWD1|RNF119

Gene ID

84231

UniProt

Q6Q0C0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

TNF receptor-associated factor 7

Target

TRAF7

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, IP, WB

Field of Research

Epigenetics, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

67-75 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC, IP, WB

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