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TPRKB antibody

Product Specifications

Background

Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t (6) A activity of the complex. TPRKB is not required for tRNA modification (By similarity) .

Synonyms

EKC/KEOPS complex subunit TPRKB|PRPK-binding protein|TP53RK-binding protein|TPRKB

Gene ID

51002

UniProt

Q9Y3C4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

TP53RK binding protein

Target

TPRKB

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

20 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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