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TOP2A antibody

Product Specifications

Background

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

Synonyms

DNA topoisomerase 2-alpha|DNA topoisomerase II, alpha isozyme|TOP2A|TOP2

Gene ID

7153

UniProt

P11388

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Topoisomerase (DNA) II alpha 170kDa

Target

TOP2A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF, IP

Field of Research

Epigenetics, Cell Division and Proliferation, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

174 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF, IP

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