TOP2A antibody
Product Specifications
Background
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .
Synonyms
DNA topoisomerase 2-alpha|DNA topoisomerase II, alpha isozyme|TOP2A|TOP2
Gene ID
7153
UniProt
P11388
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Topoisomerase (DNA) II alpha 170kDa
Target
TOP2A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Epigenetics, Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
174 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
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