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TNFAIP8 antibody

Product Specifications

Background

Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Synonyms

Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) |Head and neck tumor and metastasis-related protein|MDC-3.13|NF-kappa-B-inducible DED-containing protein (NDED) |SCC-S2|TNF-induced protein GG2-1|TNFAIP8

Gene ID

25816

UniProt

O95379

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Tumor necrosis factor, alpha-induced protein 8

Target

TNFAIP8

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Stem Cells, Immunology, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

21-23 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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