STING1 antibody

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Stimulator of interferon genes protein (hSTING) |Endoplasmic reticulum interferon stimulator (ERIS) |Mediator of IRF3 activation (hMITA) |Transmembrane protein 173|STING1|ERIS|MITA|STING|TMEM173