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ANO1 antibody

Product Specifications

Background

ANO1 also named as DOG1, ORAOV2, TAOS2 and TMEM16A, acts as a calcium-activated chloride channel. It is required for normal tracheal development. ANO1 (or DOG1) is used as an aid in the identification and diagnosis of gastrointestinal stromal tumors (GIST) within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified pathologist. The immunogen is the C-terminal of ANO1. This antibody can recognize isoform1 and isoform2 of human ANO1.

Synonyms

Anoctamin-1|Discovered on gastrointestinal stromal tumors protein 1|Oral cancer overexpressed protein 2|Transmembrane protein 16A|Tumor-amplified and overexpressed sequence 2|ANO1|DOG1|ORAOV2|TAOS2|TMEM16A

Gene ID

55107

UniProt

Q5XXA6

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Transmembrane protein 16A

Target

ANO1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC

Field of Research

Cancer, Immunology, Developmental biology

Purification

Immunogen affinity purified

Dilution

IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC

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