ANO1 antibody
Product Specifications
Background
ANO1 also named as DOG1, ORAOV2, TAOS2 and TMEM16A, acts as a calcium-activated chloride channel. It is required for normal tracheal development. ANO1 (or DOG1) is used as an aid in the identification and diagnosis of gastrointestinal stromal tumors (GIST) within the context of an antibody panel, the patient’s clinical history, and other diagnostic tests evaluated by a qualified pathologist. The immunogen is the C-terminal of ANO1. This antibody can recognize isoform1 and isoform2 of human ANO1.
Synonyms
Anoctamin-1|Discovered on gastrointestinal stromal tumors protein 1|Oral cancer overexpressed protein 2|Transmembrane protein 16A|Tumor-amplified and overexpressed sequence 2|ANO1|DOG1|ORAOV2|TAOS2|TMEM16A
Gene ID
55107
UniProt
Q5XXA6
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Transmembrane protein 16A
Target
ANO1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Cancer, Immunology, Developmental biology
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC
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