TLR7 antibody
Product Specifications
Background
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) .
Synonyms
Toll-like receptor 7|TLR7
Gene ID
51284
UniProt
Q9NYK1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Toll-like receptor 7
Target
TLR7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:600; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
121 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
861-1049aa
Curated Selection
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