TLK1 antibody
Product Specifications
Background
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.
Synonyms
Serine/threonine-protein kinase tousled-like 1|PKU-beta|Tousled-like kinase 1|TLK1|KIAA0137
Gene ID
9874
UniProt
Q9UKI8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tousled-like kinase 1
Target
TLK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
031502-ML405 100 µL
ABL, phosphorylated (Y412) (p150, Proto-oncogene c-Abl, Abelson murine leukemia viral oncogene homolog 1, Tyrosine-protein kinase ABL1, JTK7, ABL, ABL1) (MaxLight 405) discontinued
Sign In for Pricing
View Details R8693h 1 Each
Human PSCA / Prostate stem cell antigen Recombinant Protein
Sign In for Pricing
View Details