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TIMM13 antibody

Product Specifications

Background

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins.

Synonyms

Mitochondrial import inner membrane translocase subunit Tim13|TIMM13|TIM13B|TIMM13A|TIMM13B

Gene ID

26517

UniProt

Q9Y5L4

Host

Rabbit

Reactivity

Human

Immunogen

Translocase of inner mitochondrial membrane 13 homolog (yeast)

Target

TIMM13

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IF

Field of Research

Neuroscience

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

11 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IF

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