TFAP2B antibody
Product Specifications
Background
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
Synonyms
Transcription factor AP-2-beta (AP2-beta)|Activating enhancer-binding protein 2-beta|TFAP2B
Gene ID
7021
UniProt
Q92481
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
transcription factor AP-2 beta(activating enhancer binding protein 2 beta)
Target
TFAP2B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Cancer, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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