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TDRD5 antibody

Product Specifications

Background

Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity) .

Synonyms

Tudor domain-containing protein 5|TDRD5|TUDOR3

Gene ID

163589

UniProt

Q8NAT2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Tudor domain containing 5

Target

TDRD5

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

116 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

Immunogen Sequence

1-283aa

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