TDRD3 antibody
Product Specifications
Background
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation(H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs(GAR) in dimethylarginine-containing proteins.
Synonyms
Tudor domain-containing protein 3|TDRD3
Gene ID
81550
UniProt
Q9H7E2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
tudor domain containing 3
Target
TDRD3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
73 kDa;83 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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