TAX1BP1 antibody
Product Specifications
Background
TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms with MW 65-68 kDa and 86-91 kDa.
Synonyms
Tax1-binding protein 1|TRAF6-binding protein|TAX1BP1|T6BP
Gene ID
8887
UniProt
Q86VP1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tax1 (human T-cell leukemia virus type I) binding protein 1
Target
TAX1BP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa, 85 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
601-789aa
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15326470 1 Vial
Lentiviral human RCOR3 shRNA (UAS) - Lentiviral human RCOR3 shRNA (UAS) plasmid
Ask
View Details 
MBS7179963 Inquire
Rabbit anti-Schizosaccharomyces pombe (strain 972/24843)(Fission yeast) SPCC18.20 Polyclonal Antibody
Ask
View Details MBS6333348-01 0.1 mL
PHF20L1, CT (PHF20L1, PHD finger protein 20-like protein 1) (MaxLight 405)
Ask
View Details MBS6333348-02 5x 0.1 mL
PHF20L1, CT (PHF20L1, PHD finger protein 20-like protein 1) (MaxLight 405)
Ask
View Details 