TAOK3 antibody
Product Specifications
Background
Serine/threonine-protein kinase that acts as a regulator of the p38/MAPK14 stress-activated MAPK cascade and of the MAPK8/JNK cascade. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of upstream MAP2K3 and MAP2K6 kinases. Inhibits basal activity of MAPK8/JNK cascade and diminishes its activation in response epidermal growth factor(EGF).
Synonyms
Serine/threonine-protein kinase TAO3|Cutaneous T-cell lymphoma-associated antigen HD-CL-09 (CTCL-associated antigen HD-CL-09)|Dendritic cell-derived protein kinase|JNK/SAPK-inhibitory kinase|Jun kinase-inhibitory kinase|Kinase from chicken homolog A (hKFC-A)|Thousand and one amino acid protein 3|TAOK3|DPK|JIK|KDS|MAP3K18
Gene ID
51347
UniProt
Q9H2K8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
TAO kinase 3
Target
TAOK3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100-105 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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