Talpid3 antibody

Product Specifications

Background

Required for ciliogenesis and sonic hedgehog/SHH signaling (PubMed:21750036) . Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (By similarity) . Involved in regulation of cell intracellular organization (PubMed:26386247) . Involved in regulation of cell polarity (By similarity) . Required for asymmetrical localization of CEP120 to daughter centrioles (PubMed:25251415) .

Synonyms

Protein TALPID3|Talpid3

Gene ID

76967

UniProt

E9PV87

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

KIAA0586

Target

Talpid3

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC

Purification

Immunogen affinity purified

Dilution

IHC: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC

Curated Selection

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