Talpid3 antibody
Product Specifications
Background
Required for ciliogenesis and sonic hedgehog/SHH signaling(PubMed:21750036). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation(By similarity). Involved in regulation of cell intracellular organization(PubMed:26386247). Involved in regulation of cell polarity(By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles(PubMed:25251415).
Synonyms
Protein TALPID3|Talpid3
Gene ID
76967
UniProt
E9PV87
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
KIAA0586
Target
Talpid3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Purification
Immunogen affinity purified
Dilution
IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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